Alin Bogdan DEACĂNU1*, Doina NIŢESCU1, Răzvan Adrian IONESCU1,2
Abstract. Polymyalgia rheumatica (PMR) is a common inflammatory condition affecting elderly patients, often presenting with non-specific symptoms that complicate diagnosis. We report the case of a 75-year-old female with a history of PMR and multiple comorbidities, admitted for dysphagia and vesiculobullous skin and mucosal lesions. Despite inconclusive histopathological findings and limited access to specific autoantibody testing, the clinical presentation raised suspicion of a bullous autoimmune dermatosis, possibly drug-induced. The patient responded favorably to immunosuppressive and antimicrobial therapy. This case highlights the diagnostic challenges in overlapping autoimmune syndromes and underscores the importance of interdisciplinary management in complex immunomodulated patients.
Keywords: polymyalgia rheumatica, bullous dermatoses, autoimmune skin disease, pemphigoid, immunosuppression.
DOI 10.56082/annalsarscimed.2025.1.69
¹ Department of Internal Medicine III, Colentina Clinical Hospital, Bucharest, Romania
2 University of Medicine and Pharmacy Carol Davila Bucharest, Romania
* Correspondence: Alin Bogdan Deacănu, Department of Internal Medicine III, Colentina Clinical Hospital, Bucharest, Romania; mail: alin-bogdan.deacanu@rez.umfcd.ro.
PUBLISHED in Annals of the Academy of Romanian Scientists Series of Medicine, Volume 6, Issue 1
ISSN-L 2668-8816 ONLINE ISSN 2668-8816
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It is a biannual, open-access journal edited by the Academy of Romanian Scientists and published by the Academy of Romanian Scientists Publishing House.