Ana-Lucia BLENDEA1, Alin CIOBICA2, Ioan GOTCA3, Andreea GHERASIM4, Ionuț RAȚA5, Eman H. RASHWAN6
Abstract. The emerging field of psychobiotics is transforming our understanding of the gut-brain connection, revealing how diet and specific microbial strains influence mental health (Dinan et al., 2013). This article explores the latest scientific advancements in psychobiotics, highlighting their potential to modulate mood, cognition, and emotional well-being through gut microbiota interactions (Sarkar et al., 2016). We examine the mechanisms by which psychobiotic bacteria and dietary interventions affect neurotransmitter production, inflammation, and the gut-brain axis (Kelly et al., 2016). Additionally, we discuss the clinical implications of psychobiotic therapies for conditions such as anxiety, depression, and stress-related disorders. As research in this field progresses, psychobiotics may pave the way for novel, microbiome-based mental health treatments, marking a paradigm shift in neuroscience and nutritional psychiatry (Cryan & Dinan, 2012).
Keywords: psychobiotics, gut-brain axis, microbiome, mental health, nutritional psychiatry
DOI 10.56082/annalsarscibio.2025.1.248
1Student at Nutrition and Dietetics, UMF Iasi, University of Medicine and Pharmacy
2Ciobica Alin, Habil. PhD Principal Investigator Alexandru Ioan Cuza University, Faculty of Biology, Iasi, Romania, Romanian Academy of Sciences
3Doctor of Medicine, CSM Iasi, Socola Psychiatry Institute
4Internal Medicine II Department, Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, Romania
5Student at Nutrition and Dietetics, UMF Iasi, University of Medicine and Pharmacy
6Faculty of veterinary Medicine, Cairo University, Cairo, Egypt
PUBLISHED in Annals Academy of Romanian Scientists Series on Biological Sciences, Volume 14 no 1, 2025