Natural
Neuroimunomodulation in Coronavirus Infection
Gheorghe
GIURGIU*1, Manole COJOCARU2
1 Deniplant-Aide Sante Medical Center,
Biomedicine, Bucharest, Romania
2 Titu Maiorescu University, Faculty of
Medicine, Bucharest, Romania
* Corresponding
author e-mail: deniplant@gmail.com
Abstract
Dysbiosis of the nasopharyngeal microbiome
attracts dysbiosis of the intestinal microbiome and activation of the
intestinal microbiome-brain axis. If the first sign of the disease is
quickly intervened with the modulation of the activity of the microbiome,
implicitly of the immune system (neuroimmunomodulation), the appearance of the
disease is eliminated. There is the microbiome: buccal, nasal, intestinal,
cardiac, cutaneous and even the microbiome in the brain with which Covid-19
interacts. When the evolution is complicated, it is necessary to intervene
with drug treatment to support the affected organs. Although there is also
renal impairment, no coronaviruses or traces were found in the patients'
urine. Knowing that the infection also causes digestive symptoms,
coronaviruses have been shown in faeces. It is
said that in 1-2% of cases Covid-19 reaches the bloodstream. The
microbiome is essential for promoting immune function to prevent and combat
disease. Specifically, with regard to viral infections, there must be an
adequate immune response to protect the body. The intestinal microbiota with
low diversity will consequently lead to a deficient immune function. The
microbiota, the intestine and the brain communicate through the
microbiota-intestine-brain axis in a bidirectional way. We assume that the
Covid-19 virus creates a dysbiosis of the intestinal microbiome. A healthy gut
microbiome is crucial in creating an adequate response to coronavirus. A
diverse microbiome is a healthy microbiome, which contains many different
species that each play a role in immunity and health. The motivation of
the project is the study of the influence of the intestinal microbiota in terms
of health and the appearance of symptoms in Covid-19 infection. With the
help of Deniplant brand natural remedies, the authors
have developed several products for autoimmune, metabolic and neurological
diseases that act as immunomodulators of the human microbiome.
Key words: intestinal microbiome, Covid-19 infection, natural remedies, natural
neuroimmunomodulation.
DOI https://doi.org/10.56082/annalsarscibio.2020.2.80