Animal Models in the Microbiota vs.
Irritable Bowel
Syndrome Manifestations - Preliminary Aspects
on the Probiotic Therapy in Irritable Bowel Syndrome
Ovidiu-Dumitru Ilie1, Ioana-Miruna Balmus1,2, Samson Guenne3, Mahmoud a. ali4, Alin Ciobica5,6
1Department of Research, Faculty of
Biology, “Alexandru Ioan Cuza” University of Iasi, Carol I Avenue, 20A, 700490
Iasi, Romania
2Interdisciplinary Research
Department–Field Science, “Alexandru Ioan Cuza” University of Iasi, Carol I
Avenue, 20A, 700490 Iasi, Romania
3Laboratory of Applied Biochemistry
and Chemistry, University Joseph KI-ZERBO, 03 BP 7021 Ouagadougou 03, Burkina
Faso
4 Biotechnology Program
, Faculty of Agriculture, Cairo
University, Giza, Egypt
5Romanian Academy, Iasi Branch, Nr.
8, Carol I Avenue, no. 8, 700490 Iasi, Romania
6Academy of Romanian Scientists, Splaiul Independentei nr. 54, sector 5, 050094 Bucuresti, Romania
* Corresponding author e-mail: alin.ciobica@gmail.com
Abstract
Irritable bowel
syndrome (IBS) is a common functional disorder that affects the digestive
system and especially the large intestine, expressed mainly through symptoms
including diarrhea, constipation, abdominal pain, bloating and cramping. It
could be associated with mood disorders including depression and anxiety.
Additionally one of the causes of IBS could be a change in gut microflora.
Also, could exert a significant role in this context and their potential
benefits in maintaining a healthy gut. Here we discussed the possible role of
therapy with probiotics in IBS, as well as some important animal models
regarding this topic.
Keywords: Irritable
bowel syndrome (IBS), Microbiome, Gut-brain axis, Probiotics
DOI https://doi.org/10.56082/annalsarscibio.2020.1.80
